SciFit's Thermabolic is a synergistic combination of the herbs Coleus Forskohlii and Guggul Lipid Extract designed to support healthy thyroid function. These two combine for a safe, effective and powerful fat burning effect! Increase metabolism and burn off unwanted pounds! Sci Fit's Thermabolic is a synergistic combination of the herbs Coleus Forskohlii and Guggul Lipid Extract designed to enhance weight loss as well as promote healthy thyroid function. The Thyroid gland is the primary metabolic regulator in our body. The Thyroid gland produces T4 and T3 with T4 being converted into T3 in the tissue. The amount of T4 which is produced, released, and subsequently converted into T3 is the critical factor in determining the amount of metabolic activity in the body. T3 is responsible for increasing metabolic activity in virtually all tissues in the body, increasing the number of mitochondria, increasing protein synthesis, stimulating carbohydrate metabolism, accelerating fat metabolism, decreasing cholesterol levels, etc? Thermabolic provides 200 mg. of Coleus Forskohlii per capsule providing 20 mg. of the active ingredient Coleolin. Coleus Forskohlii activates the enzyme adenyl cyclase which increases the amount of Cyclic AMP (cAMP). Cyclic AMP is a very important cell regulating compound which is involved in numerous cellular functions such as: increasing the force of heart muscle contraction, increasing insulin secretion, increasing fat metabolism, and improving thyroid function. Thermabolic provides 200 mg. of Guggul Lipid Extract per capsule which contains 20 mg. of the active ingredient Guggulsterones. Guggul is said to assist in the lowering of Cholesterol, help to detoxify tissues in the body, as well as promote healthy thyroid function.